Moderna reported that laboratory tests proved that the booster shot half-dose increased 37-fold the levels of the so-called neutralizing antibody, which are able to combat omicron.
The company stated that a full dose booster could trigger an 83fold increase in antibodies, but with more side effects. Half-dose shots can be used to boost Moderna, but people suffering from a weak immune system should get a third full dose shot.
Moderna announced the preliminary laboratory data in a press release and it hasn’t yet undergone scientific review. The U.S. National Institutes of Health announced a similar increase in test results last week.
Pfizer’s testing likewise found its COVID-19 vaccine triggered a similarly big jump in omicron-fighting antibodies. Moderna’s and Pfizer’s vaccines, which are both made using mRNA technology with the coronavirus, are being used worldwide.
Together, the available evidence backs health authorities” increasing pleas for people to get their boosters as soon as they’re eligible.
Antibody levels predict how well a vaccine may prevent infection with the coronavirus but they are just one layer of the immune system’s defenses. Another study suggests that vaccines should provide good protection against severe diseases in the event of an outbreak.
Both Moderna and Pfizer are developing shots to better match the omicron variant in case they’re needed.
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. All content remains the responsibility of the Associated Press.